Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs.

Ítems similars

• Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology.
  per: Wages, D S, et al.
  Publicat: (1992)
• The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain
  per: Salinas-Garcia, M. Carmen, et al.
  Publicat: (2021)
• Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.
  per: Hirai, H, et al.
  Publicat: (1990)
• Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src.
  per: Superti-Furga, G, et al.
  Publicat: (1993)
• Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3
  per: Sengupta, S, et al.
  Publicat: (2017)