Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.

Lignende værker

• Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain.
  af: O'Brien, M C, et al.
  Udgivet: (1990)
• Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells.
  af: Hirai, H, et al.
  Udgivet: (1990)
• A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner.
  af: Verderame, M F, et al.
  Udgivet: (1989)
• Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides.
  af: Bibbins, K B, et al.
  Udgivet: (1993)
• Inhibition of epidermal growth factor receptor biosynthesis caused by the src oncogene product, pp60v-src.
  af: Wasilenko, W J, et al.
  Udgivet: (1990)