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The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain
Src kinase belongs to the family of Src-related nonreceptor tyrosine kinases. Because of its physiological role in cell growth and proliferation, its activity is strictly controlled by several mechanisms. Nevertheless, in viral Src kinase (v-Src) some of these mechanisms fail, and its uncontrolled a...
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| Publicado no: | Acta Crystallogr D Struct Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171063/ https://ncbi.nlm.nih.gov/pubmed/34076598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798321004344 |
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