Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms.

Glucocorticoids inhibit proliferation of many cell types, but the events leading from the activated glucocorticoid receptor (GR) to growth arrest are not understood. Ectopic expression and activation of GR in human osteosarcoma cell lines U2OS and SAOS2, which lack endogenous receptors, result in a...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Rogatsky, I, Trowbridge, J M, Garabedian, M J
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232171/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9154817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.6.3181
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