Proteolysis by calpains: a possible contribution to degradation of p53.

p53 is a short-lived transcription factor that is frequently mutated in tumor cells. Work by several laboratories has already shown that the ubiquitin-proteasome pathway can largely account for p53 destruction, at least under specific experimental conditions. We report here that, in vitro, wild-type...

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Bibliographic Details
Main Authors: Pariat, M, Carillo, S, Molinari, M, Salvat, C, Debüssche, L, Bracco, L, Milner, J, Piechaczyk, M
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC232132/
https://ncbi.nlm.nih.gov/pubmed/9111352
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