PEST motifs are not required for rapid calpain-mediated proteolysis of c-fos protein.

Cytoplasmic degradation of c-fos protein is extremely rapid. Under certain conditions, it is a multi-step process initiated by calcium-dependent and ATP-independent proteases called calpains. PEST motifs are peptide regions rich in proline, glutamic acid/aspartic acid and serine/threonine residues,...

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Detalhes bibliográficos
Principais autores: Carillo, S, Pariat, M, Steff, A m, Jariel-Encontre, I, Poulat, F, Berta, P, Piechaczyk, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1216890/
https://ncbi.nlm.nih.gov/pubmed/8546691
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