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SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene.

The identification of mutations in the SRY-related SOX9 gene in patients with campomelic dysplasia, a severe skeletal malformation syndrome, and the abundant expression of Sox9 in mouse chondroprogenitor cells and fully differentiated chondrocytes during embryonic development have suggested the hypo...

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Udgivet i:Mol Cell Biol
Principais autores: Lefebvre, V, Huang, W, Harley, V R, Goodfellow, P N, de Crombrugghe, B
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.2336
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