Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA.

Human replication protein A (RP-A) (also known as human single-stranded DNA binding protein, or HSSB) is a multisubunit complex involved in both DNA replication and repair. Potentially important to both these functions, it is also capable of complex formation with the tumor suppressor protein p53. H...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Miller, S D, Moses, K, Jayaraman, L, Prives, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.2194
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