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Stimulation of polyomavirus DNA replication by wild-type p53 through the DNA-binding site.

The tumor suppressor p53 possesses characteristics of a transcription factor; it binds to specific DNA sequences and activates transcription from various promoters. Here we found that murine wild-type p53 stimulated not only transcription but also polyomavirus (Py) DNA replication in a sequence-depe...

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Main Authors: Kanda, T, Segawa, K, Ohuchi, N, Mori, S, Ito, Y
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC358632/
https://ncbi.nlm.nih.gov/pubmed/8139565
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