The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2.
The interaction of the retinoblastoma susceptibility gene product (Rb)-related p107 protein with the E2F transcription factor in S-phase cells facilitates the formation of a multicomponent complex also containing cyclin A and the p33cdk2 kinase. We have created a series of p107 mutants to assess the...
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| Опубликовано в:: | Mol Cell Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1995
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7799940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.1.338 |
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