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The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2.

The interaction of the retinoblastoma susceptibility gene product (Rb)-related p107 protein with the E2F transcription factor in S-phase cells facilitates the formation of a multicomponent complex also containing cyclin A and the p33cdk2 kinase. We have created a series of p107 mutants to assess the...

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Detalles Bibliográficos
Autores principales: Smith, E J, Nevins, J R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC231964/
https://ncbi.nlm.nih.gov/pubmed/7799940
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