Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.

F9 embryonic teratocarcinoma stem cells differentiate into an epithelial cell type called extraembryonic endoderm when treated with retinoic acid (RA), a derivative of retinol (vitamin A). This differentiation is presumably mediated through the actions of retinoid receptors, the RARs and RXRs. To de...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Boylan, J F, Lufkin, T, Achkar, C C, Taneja, R, Chambon, P, Gudas, L J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.843
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