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Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.

Retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers bind to cognate response elements in vitro more efficiently than do RAR or RXR homodimers, and both RAR and RXR partners have been shown to activate various promoters in transiently transfected cells. We have now investigated whethe...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Roy, B, Taneja, R, Chambon, P
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.6481
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