The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest.

Interleukin-1 (IL-1) is a growth arrest signal for diverse human tumor cell lines. We report here that the action of this cytokine in melanoma cells is associated with induction of EGR-1, a zinc finger protein that activates gene transcription. Both growth arrest and EGR-1 are induced via the type I...

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Bibliografiska uppgifter
Huvudupphovsmän: Sells, S F, Muthukumar, S, Sukhatme, V P, Crist, S A, Rangnekar, V M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC231931/
https://ncbi.nlm.nih.gov/pubmed/7823937
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