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The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest.

Interleukin-1 (IL-1) is a growth arrest signal for diverse human tumor cell lines. We report here that the action of this cytokine in melanoma cells is associated with induction of EGR-1, a zinc finger protein that activates gene transcription. Both growth arrest and EGR-1 are induced via the type I...

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Udgivet i:Mol Cell Biol
Principais autores: Sells, S F, Muthukumar, S, Sukhatme, V P, Crist, S A, Rangnekar, V M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823937/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.682
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