The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest.

Interleukin-1 (IL-1) is a growth arrest signal for diverse human tumor cell lines. We report here that the action of this cytokine in melanoma cells is associated with induction of EGR-1, a zinc finger protein that activates gene transcription. Both growth arrest and EGR-1 are induced via the type I...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Sells, S F, Muthukumar, S, Sukhatme, V P, Crist, S A, Rangnekar, V M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.682
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