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A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene.

Enhancer elements have been shown to affect the probability of a gene establishing an active transcriptional state and suppress the silencing of reporter genes in cell lines, but their effect in transgenic mice has been obscured by the use of assays that do not assess expression on a cell-by-cell ba...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Sutherland, H G, Martin, D I, Whitelaw, E
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032288/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1607
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