Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.

Mice made insulin receptor substrate 1 (IRS-1) deficient by targeted gene knockout exhibit growth retardation and abnormal glucose metabolism due to resistance to the actions of insulin-like growth factor 1 (IGF-1) and insulin (E. Araki et al., Nature 372:186-190, 1994; H. Tamemoto et al., Nature 37...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Brüning, J C, Winnay, J, Cheatham, B, Kahn, C R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231877/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1513
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!