Frequent aberrant methylation of p16INK4a in primary rat lung tumors.

The p16INK4a (p16) tumor suppressor gene is frequently inactivated by homozygous deletion or methylation of the 5' CpG island in cell lines derived from human non-small-cell lung cancers. However, the frequency of dysfunction in primary tumors appears to be significantly lower than that in cell...

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Bibliografske podrobnosti
Main Authors: Swafford, D S, Middleton, S K, Palmisano, W A, Nikula, K J, Tesfaigzi, J, Baylin, S B, Herman, J G, Belinsky, S A
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC231861/
https://ncbi.nlm.nih.gov/pubmed/9032263
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