Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.

Ítems similars

• Tight Binding of the Phosphorylated α Subunit of Initiation Factor 2 (eIF2α) to the Regulatory Subunits of Guanine Nucleotide Exchange Factor eIF2B Is Required for Inhibition of Translation Initiation
  per: Krishnamoorthy, Thanuja, et al.
  Publicat: (2001)
• Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation.
  per: Vazquez de Aldana, C R, et al.
  Publicat: (1994)
• Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2.
  per: Yang, W, et al.
  Publicat: (1996)
• An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation
  per: Singh, Chingakham Ranjit, et al.
  Publicat: (2006)
• eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine–nucleotide exchange
  per: Pavitt, Graham D., et al.
  Publicat: (1998)