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Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences.

African trypanosomes undergo antigenic variation of their variant surface glycoprotein (VSG) coat to avoid immune system-mediated killing by their mammalian host. An important mechanism for switching the expressed VSG gene is the duplicative transposition of a silent VSG gene into one of the telomer...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: McCulloch, R, Rudenko, G, Borst, P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9001237/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.2.833
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