Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences.
African trypanosomes undergo antigenic variation of their variant surface glycoprotein (VSG) coat to avoid immune system-mediated killing by their mammalian host. An important mechanism for switching the expressed VSG gene is the duplicative transposition of a silent VSG gene into one of the telomer...
Na minha lista:
| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1997
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9001237/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.2.833 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|