Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigens

Summary: Trypanosoma brucei evades mammalian immunity by using recombination to switch its surface-expressed variant surface glycoprotein (VSG), while ensuring that only one of many subtelomeric multigene VSG expression sites are transcribed at a time. DNA repair activities have been implicated in t...

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Bibliografiske detaljer

Principais autores:	Jennifer Ann Black, Kathryn Crouch, Leandro Lemgruber, Craig Lapsley, Nicholas Dickens, Luiz R.O. Tosi, Jeremy C. Mottram, Richard McCulloch
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2020-01-01
Serier:	Cell Reports
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2211124719317061
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