The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.

類似資料

• Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif.
  著者:: Phelan, M L, 等
  出版事項: (1995)
• Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
  著者:: Monica, K, 等
  出版事項: (1994)
• The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.
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  出版事項: (1995)
• Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
  著者:: Lu, Q, 等
  出版事項: (1995)
• Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1
  著者:: Knoepfler, Paul S., 等
  出版事項: (1997)