The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

Eitemau Tebyg

• Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex.
  gan: Lu, Q, et al.
  Cyhoeddwyd: (1996)
• Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
  gan: Lu, Q, et al.
  Cyhoeddwyd: (1995)
• Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif.
  gan: Knoepfler, P S, et al.
  Cyhoeddwyd: (1996)
• A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1.
  gan: Knoepfler, P S, et al.
  Cyhoeddwyd: (1999)
• Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1
  gan: Knoepfler, Paul S., et al.
  Cyhoeddwyd: (1997)