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The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

The vertebrate Hox genes, which represent a subset of all homeobox genes, encode proteins that regulate anterior-posterior positional identity during embryogenesis and are cognates of the Drosophila homeodomain proteins encoded by genes composing the homeotic complex (HOM-C). Recently, we demonstrat...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Knoepfler, P S, Kamps, M P
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1995
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230833/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.10.5811
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