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The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif.

Progression through the cell cycle is dependent on the sequential expression of cyclins, which combine with cyclin-dependent kinases (cdks) to form active kinases. The transition from G1 to S phase is dependent on D cyclins in complex with cdk4 or cdk6 and cyclin E complexed with cdk2. One target of...

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Pubblicato in:Mol Cell Biol
Autori principali: Chow, K N, Starostik, P, Dean, D C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7173
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