The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain.

Ítems similars

• Point mutations in the Drosophila hairy gene demonstrate in vivo requirements for basic, helix-loop-helix, and WRPW domains.
  per: Wainwright, S M, et al.
  Publicat: (1992)
• Members of the HRT family of basic helix–loop–helix proteins act as transcriptional repressors downstream of Notch signaling
  per: Nakagawa, Osamu, et al.
  Publicat: (2000)
• Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif.
  per: Fisher, F, et al.
  Publicat: (1992)
• Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix–loop–helix repressor of neuronal differentiation
  per: Ström, Anders, et al.
  Publicat: (1997)
• An overview of the basic helix-loop-helix proteins
  per: Jones, Susan
  Publicat: (2004)