The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif.
Progression through the cell cycle is dependent on the sequential expression of cyclins, which combine with cyclin-dependent kinases (cdks) to form active kinases. The transition from G1 to S phase is dependent on D cyclins in complex with cdk4 or cdk6 and cyclin E complexed with cdk2. One target of...
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| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7173 |
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