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Constitutive activation of the RON gene promotes invasive growth but not transformation.

MET, RON, and SEA are members of a gene family encoding tyrosine kinase receptors with distinctive properties. Besides mediating growth, they control cell dissociation, motility ("scattering"), and formation of branching tubules. While there are transforming counterparts of MET and SEA, no oncogenic...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Santoro, M M, Collesi, C, Grisendi, S, Gaudino, G, Comoglio, P M
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7072
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