Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing

Abstract Background Altered expression of receptor tyrosine kinases (RTKs) is a major driver of growth and metastasis of cancers. Recepteur d’origine nantais (RON) receptor is a single-pass transmembrane RTK aberrantly expressed in a number of cancers. Efforts to block deregulated RON signaling in t...

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Detalhes bibliográficos

Principais autores:	Soundararajan Krishnaswamy, Abdul Khader Mohammed, Gyanendra Tripathi, Majed S. Alokail, Nasser M. Al-Daghri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-11-01
Colecção:	BMC Cancer
Assuntos:	RON Macrophage stimulating protein Alternative splicing RON isoform Receptor tyrosine kinase Lung cancer
Acesso em linha:	http://link.springer.com/article/10.1186/s12885-017-3747-x
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