Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing

Abstract Background Altered expression of receptor tyrosine kinases (RTKs) is a major driver of growth and metastasis of cancers. Recepteur d’origine nantais (RON) receptor is a single-pass transmembrane RTK aberrantly expressed in a number of cancers. Efforts to block deregulated RON signaling in t...

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Autores principales:	Soundararajan Krishnaswamy, Abdul Khader Mohammed, Gyanendra Tripathi, Majed S. Alokail, Nasser M. Al-Daghri
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2017-11-01
Colección:	BMC Cancer
Materias:	RON Macrophage stimulating protein Alternative splicing RON isoform Receptor tyrosine kinase Lung cancer
Acceso en línea:	http://link.springer.com/article/10.1186/s12885-017-3747-x
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