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Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing

Abstract Background Altered expression of receptor tyrosine kinases (RTKs) is a major driver of growth and metastasis of cancers. Recepteur d’origine nantais (RON) receptor is a single-pass transmembrane RTK aberrantly expressed in a number of cancers. Efforts to block deregulated RON signaling in t...

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Principais autores: Soundararajan Krishnaswamy, Abdul Khader Mohammed, Gyanendra Tripathi, Majed S. Alokail, Nasser M. Al-Daghri
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-11-01
Serier:BMC Cancer
Fag:
RON
Macrophage stimulating protein
Alternative splicing
RON isoform
Receptor tyrosine kinase
Lung cancer
Online adgang:http://link.springer.com/article/10.1186/s12885-017-3747-x
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