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Constitutive activation of the RON gene promotes invasive growth but not transformation.

MET, RON, and SEA are members of a gene family encoding tyrosine kinase receptors with distinctive properties. Besides mediating growth, they control cell dissociation, motility ("scattering"), and formation of branching tubules. While there are transforming counterparts of MET and SEA, no oncogenic...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Santoro, M M, Collesi, C, Grisendi, S, Gaudino, G, Comoglio, P M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7072
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