c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein.
The c-ABL tyrosine kinase is activated following either the loss or mutation of its Src homology domain 3 (SH3), resulting in both increased autophosphorylation and phosphorylation of cellular substrates and cellular transformation. This suggests that the SH3 domain negatively regulates c-ABL kinase...
Na minha lista:
| Publicado no: | Mol Cell Biol |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1996
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7054 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|