c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein.
The c-ABL tyrosine kinase is activated following either the loss or mutation of its Src homology domain 3 (SH3), resulting in both increased autophosphorylation and phosphorylation of cellular substrates and cellular transformation. This suggests that the SH3 domain negatively regulates c-ABL kinase...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7054 |
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