c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein.

The c-ABL tyrosine kinase is activated following either the loss or mutation of its Src homology domain 3 (SH3), resulting in both increased autophosphorylation and phosphorylation of cellular substrates and cellular transformation. This suggests that the SH3 domain negatively regulates c-ABL kinase...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Zhu, J, Shore, S K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.7054
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