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Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint.

The commitment of mammalian cells in late G1 to replicate the genome and divide in response to mitogenic growth factors operating via tyrosine kinase receptors depends on phosphorylation of the retinoblastoma protein (pRb), a process controlled by cyclin D-associated cyclin-dependent kinases (cdks)...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Lukas, J, Bartkova, J, Bartek, J
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231695/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6917
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