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Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint.

The commitment of mammalian cells in late G1 to replicate the genome and divide in response to mitogenic growth factors operating via tyrosine kinase receptors depends on phosphorylation of the retinoblastoma protein (pRb), a process controlled by cyclin D-associated cyclin-dependent kinases (cdks)...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Lukas, J, Bartkova, J, Bartek, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231695/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.12.6917
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