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An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity.

We have identified alternatively spliced isoforms of murine Pax-3 and Pax-7 which differ by the presence or absence of a single glutamine residue in a linker region which separates two distinct DNA-binding subdomains within the paired domain. By reverse transcription-PCR, these isoforms of Pax-3 and...

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Bibliografski detalji
Glavni autori: Vogan, K J, Underhill, D A, Gros, P
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC231670/
https://ncbi.nlm.nih.gov/pubmed/8943322
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