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Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.

There is increasing evidence that cell cycle transit is potentially lethal, with survival depending on the activation of metabolic pathways which block apoptosis. However, the identities of those pathways coupling cell cycle transit to survival remain undefined. Here we show that the eukaryotic tran...

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Autori principali: Polunovsky, V A, Rosenwald, I B, Tan, A T, White, J, Chiang, L, Sonenberg, N, Bitterman, P B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC231659/
https://ncbi.nlm.nih.gov/pubmed/8887686
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