Loss of heterozygosity and base substitution at the APRT locus in mismatch-repair-proficient and -deficient colorectal carcinoma cell lines.

We determined the nature of mutations occurring at the autosomal APRT locus in mismatch-repair-proficient and -deficient colorectal carcinoma cell lines. The analysis of mutations that result in APRT deficiency in a mismatch-repair-deficient strain of DLD-1 heterozygous for this locus enabled us to...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Phear, G, Bhattacharyya, N P, Meuth, M
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6516
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