Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR.

The interferon-induced RNA-dependent protein kinase PKR is found in cells in a latent state. In response to the binding of double-stranded RNA, the enzyme becomes activated and autophosphorylated on several serine and threonine residues. Consequently, it has been postulated that autophosphorylation...

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Main Authors: Taylor, D R, Lee, S B, Romano, P R, Marshak, D R, Hinnebusch, A G, Esteban, M, Mathews, M B
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC231632/
https://ncbi.nlm.nih.gov/pubmed/8887659
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