Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR.

The interferon-induced RNA-dependent protein kinase PKR is found in cells in a latent state. In response to the binding of double-stranded RNA, the enzyme becomes activated and autophosphorylated on several serine and threonine residues. Consequently, it has been postulated that autophosphorylation...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Taylor, D R, Lee, S B, Romano, P R, Marshak, D R, Hinnebusch, A G, Esteban, M, Mathews, M B
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.11.6295
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