DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences.

Purified RAG1 and RAG2 proteins can cleave DNA at V(D)J recombination signals. In dissecting the DNA sequence and structural requirements for cleavage, we find that the heptamer and nonamer motifs of the recombination signal sequence can independently direct both steps of the cleavage reaction. Prop...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Cuomo, C A, Mundy, C L, Oettinger, M A
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5683
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