DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences.
Purified RAG1 and RAG2 proteins can cleave DNA at V(D)J recombination signals. In dissecting the DNA sequence and structural requirements for cleavage, we find that the heptamer and nonamer motifs of the recombination signal sequence can independently direct both steps of the cleavage reaction. Prop...
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| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5683 |
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