DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences.
Purified RAG1 and RAG2 proteins can cleave DNA at V(D)J recombination signals. In dissecting the DNA sequence and structural requirements for cleavage, we find that the heptamer and nonamer motifs of the recombination signal sequence can independently direct both steps of the cleavage reaction. Prop...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5683 |
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