An unusual mechanism of self-primed reverse transcription requires the RNase H domain of reverse transcriptase to cleave an RNA duplex.

Eitemau Tebyg

• RNase H domain of Moloney murine leukemia virus reverse transcriptase retains activity but requires the polymerase domain for specificity.
  gan: Schultz, S J, et al.
  Cyhoeddwyd: (1996)
• Influence of the RNase H domain of retroviral reverse transcriptases on the metal specificity and substrate selection of their polymerase domains
  gan: Talele, Tanaji T, et al.
  Cyhoeddwyd: (2009)
• Structural Basis of the Allosteric Inhibitor Interaction on the HIV-1 Reverse Transcriptase RNase H domain
  gan: Christen, Martin T., et al.
  Cyhoeddwyd: (2012)
• Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.
  gan: Hostomsky, Z, et al.
  Cyhoeddwyd: (1994)
• Transcomplementation of nucleotide priming and reverse transcription between independently expressed TP and RT domains of the hepatitis B virus reverse transcriptase.
  gan: Lanford, R E, et al.
  Cyhoeddwyd: (1997)