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Effects on DNA synthesis and translocation caused by mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptase.

To determine the various roles of RNase H in reverse transcription, we generated a panel of mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptase based on sequence alignments and the crystal structures of Escherichia coli and human immunodeficiency virus type 1 RNase...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Blain, S W, Goff, S P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4440-4452.1995
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