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Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.

Biochemical and genetic evidence has implicated two families of protein tyrosine kinases (PTKs), the Src- and Syk-PTKs, in T- and B-cell antigen receptor signaling. ZAP-70 is a member of the Syk-PTKs that associates with the T-cell antigen receptor and undergoes tyrosine phosphorylation following re...

詳細記述

保存先:
書誌詳細
主要な著者: Kong, G, Dalton, M, Wardenburg, J B, Straus, D, Kurosaki, T, Chan, A C
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC231504/
https://ncbi.nlm.nih.gov/pubmed/8756661
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