Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.

Biochemical and genetic evidence has implicated two families of protein tyrosine kinases (PTKs), the Src- and Syk-PTKs, in T- and B-cell antigen receptor signaling. ZAP-70 is a member of the Syk-PTKs that associates with the T-cell antigen receptor and undergoes tyrosine phosphorylation following re...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Kong, G, Dalton, M, Wardenburg, J B, Straus, D, Kurosaki, T, Chan, A C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756661/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.5026
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