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Critical Role of Ser-520 Phosphorylation for Membrane Recruitment and Activation of the ZAP-70 Tyrosine Kinase in T Cells
Regulation of protein tyrosine kinases (PTKs) by tyrosine phosphorylation is well recognized; in fact, nearly all PTKs require phosphorylation of tyrosine residues in their “activation loop” for catalytic activity. In contrast, the phosphorylation of PTKs on serine and threonine residues has not bee...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC207614/ https://ncbi.nlm.nih.gov/pubmed/14560012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7667-7677.2003 |
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